Syringe Filters, 25mm, Nylon, 0.22um Pore Size. Purple Polypropylene, AQ Brand. 100/PK.
Additional Info:
The 58022-N25-C AQ™ Syringe Filters are pharmaceutical-grade, high-performance membrane filters engineered for HPLC sample preparation, sterile filtration, and dissolution testing in regulated laboratory environments. Featuring a 0.22 µm Nylon‑66 membrane, these filters deliver exceptional consistency, ultra-low adsorption, and extractable-free performance, ensuring maximum sample purity and reproducible analytical results.
The 0.22 µm pore size is optimized for sterile filtration and fine particulate removal, making these filters essential for critical applications requiring the highest level of sample clarity and protection of analytical systems.
✅ Critical Compliance Advantage (No Flush Required)
These filters are validated and certified to meet stringent regulatory requirements, including:
US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release
USP <788> for particulate matter in injectables
USP requirements for “Sterile Water for Injection”
Because of this validated performance:
✅ No initial flushing is required
✅ No need to discard the first 200 µL of filtrate
✅ Preserves valuable sample and saves analyst time
✅ Eliminates a common cause of failed methods and investigations
👉 This is a critical operational advantage for QC/QA laboratories, where regulatory compliance, reproducibility, and efficiency directly impact productivity and audit outcomes.
Performance & Design
The advanced 16-channel outlet design minimizes back pressure, allowing smooth filtration with significantly reduced hand force, improving ergonomics and throughput during repetitive workflows.
Nylon‑66 membrane chemistry offers broad compatibility with aqueous and organic HPLC solvents, while maintaining ultra-low adsorption—even for charged analytes, ensuring accurate quantitation.
The 25 mm format supports higher sample throughput, and the purple color coding enables immediate identification of 0.22 µm nylon filters.
Each package includes a Certificate of Analysis, ensuring traceability and compliance in regulated environments.
Key Features
0.22 µm Nylon‑66 Membrane (Pharma Grade)
Ideal for sterile filtration and fine particulate removal
Ensures maximum sample clarity
✅ No Initial Flush Required (Validated)
Extractable-free from first filtrate
Eliminates sample waste and variability
Ultra-Low Adsorption
Suitable for charged and sensitive analytes
Maximizes analyte recovery
Advanced 16-Channel Outlet Design
Reduces back pressure
Requires less hand force
Regulatory Compliance
Meets FDA CFR Title 21 requirements
Complies with USP <788>
Suitable for Sterile Water for Injection
Broad Solvent Compatibility
Compatible with aqueous and organic solvents
Ideal for mixed HPLC mobile phases
25 mm Diameter for High Throughput
Handles larger sample volumes
Improves lab productivity
Autoclavable & EO Sterilizable
121°C for 30 minutes or Ethylene Oxide
Color-Coded (Purple)
Identifies 0.22 µm nylon filters
Typical Applications
HPLC & UHPLC Sample Preparation – fine particulate removal prior to injection
Sterile Filtration – bacterial and particulate removal
Dissolution Testing – pharmaceutical QC and release workflows
Regulated Laboratory Methods – validated, compliant processes
Pharmaceutical Analysis – injectables and formulations
Aqueous & Organic Filtration – mixed solvent compatibility
Specifications
Filter Type: Syringe Filter (Pharma Grade)
Membrane Material: Nylon‑66
Pore Size: 0.22 µm
Diameter: 25 mm
Housing Material: Polypropylene (PP)
Color Code: Purple (0.22 µm Nylon)
Connection Type: Luer Lock / Slip
Chemical Compatibility: Aqueous and organic solvents
Extractables: None detectable (no flush required)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Certification: Certificate of Analysis included
Sterility: Non-sterile
Pack Size: 100/PK
Brand: AQ™
Resources & Ordering Options
Order Nylon‑66 syringe filters, 0.22 µm, 25 mm – 1000/case quantity
Purchase Nylon‑66 syringe filters, 0.22 µm, 25 mm – 50/pack quantity